Harnessing microRNAs to Direct Bone and Cartilage Repair
This webinar has since taken place and is now available on-demand.
About the Webinar
In part 3, of our webinar series on oligonucleotides, we will focus on modalities and discovery.
Meet Our Speaker
Andrea Lolli
Assistant Professor, Bone Tissue Engineering Research Group
Erasmus Medical Centre
Andrea Lolli is Assistant Professor in the Bone Tissue Engineering Research group at Erasmus MC University Medical Centre Rotterdam, The Netherlands. His research focuses on the development of therapeutic strategies based on non-coding RNAs for bone and cartilage regeneration.
Andrea obtained his PhD in Molecular Medicine and Pharmacology at the University of Ferrara, Italy. During this time, he developed a growing interest in the mechanisms that guide stem cell differentiation, and the application of this knowledge to regenerate cartilage and bone. In his PhD project he established gene silencing strategies using siRNAs and antimicroRNAs to induce the chondrogenic differentiation of stem cells without growth factors. In 2016 Andrea moved to the Netherlands for a postdoctoral position at Erasmus MC within the Marie Curie ITN TargetCaRe. Following-up on his work, he developed a microRNA therapy approach to enhance cartilage repair in vivo, by targeting implanted or endogenous progenitor cells with antimicroRNA-activated materials. In 2019 Andrea started his work in the Bone Tissue Engineering group. This allowed him to broaden his research focus with the study of the mechanisms of endochondral bone formation, ultimately leveraging non-coding RNA modulation for large bone defect repair.
