• STATE-OF-THE-ART FACILIY ENABLES GROWTH OF ADME-TOX SERVICES
• FASTER TURNAROUND TIMES THROUGH ADDED CAPACITY & AUTOMATION
• OPENING EVENT PLANNED FOR APRIL 2023

Hamburg, Germany, 15 February 2023:
Evotec SE (Frankfurt Stock Exchange: EVT, MDAX/TecDAX, ISIN: DE0005664809; NASDAQ: EVO) announced today that Cyprotex US, LLC, the US site of Cyprotex a wholly owned subsidiary of Evotec, has completed its relocation from Watertown, MA to a new state-of-the-art facility in Framingham, MA, paving the way for significant further growth of its ADME-Tox services business for US-based customers. 

Since the acquisition by Evotec in 2016, Cyprotex US, LLC, world leader in predictive toxicology and ADME research, has been growing its US business through partnerships with Pharma and biotech companies. The relocation of the US site to Framingham goes along with upgrades to the latest liquid handling automation and mass spectrometry technology, translating to significant efficiency gains, higher capacity, and faster turnaround times and will mirror many of the assays offered at the Alderley Park, UK site of Cyprotex Discovery Ltd. 

Further, Cyprotex’ customers and partners will stand to benefit from additional specialist services e.g. a full suite of transporter assays and a high-throughput transcriptomics offering for predicting drug-induced toxicity, which Cyprotex performs together with its parent company Evotec. With 30,000 square feet, Cyprotex’ new facility at 200 Staples Drive provides a high-throughput alternative for its partners on their doorstep. An opening event with clients will be held in April.

Dr Craig Johnstone, Chief Operating Officer of Evotec, commented: “Integrating predictive toxicology and ADME research into the R&D continuum is a priority for the cost-efficient development of new medicines. Cyprotex’ expansion into a first-class scientific facility in Framingham will benefit both existing and new clients across the US. The co-location of Cyprotex’ offering in proximity to Evotec’s US East Coast sites, especially the sample management facility in Branford, CT, further allows us to drastically reduce turnaround times.”

ABOUT CYPROTEX

Established in 1999, Cyprotex Limited was acquired by Evotec (www.evotec.com) in 2016. Cyprotex, an Evotec company, has sites at Alderley Park near Macclesfield, UK and in Framingham near Boston, USA. The company has dedicated and highly qualified employees with proven experience in a wide range of specialist techniques acquired across diverse industries. The majority of our clients focus in pharmaceutical research, however, we also support clients in the chemical, cosmetics and personal care, agrichemical and tobacco industries. Cyprotex specialises in in vitro and in silico ADME-Tox services. This includes in vitro ADME screening to support discovery projects, regulatory in vitro ADME and DDI studies during pre-clinical and clinical development, specialist mechanistic in vitro human and animal toxicity models (e.g. 3D models and MEA electrophysiology) and PBPK/QSAR modelling expertise. Further information on Cyprotex is available on our website at www.cyprotex.com.

FORWARD-LOOKING STATEMENTS 

This announcement contains forward-looking statements concerning future events, including the proposed offering and listing of Evotec’s securities. Words such as “anticipate,” “believe,” “could,” “estimate,” “expect,” “intend,” “may,” “might,” “plan,” “potential,” “should,” “target,” “would” and variations of such words and similar expressions are intended to identify forward-looking statements. Such statements include comments regarding Evotec’s expectations for revenues, Group EBITDA and unpartnered R&D expenses. These forward-looking statements are based on the information available to, and the expectations and assumptions deemed reasonable by Evotec at the time these statements were made. No assurance can be given that such expectations will prove to have been correct. These statements involve known and unknown risks and are based upon a number of assumptions and estimates, which are inherently subject to significant uncertainties and contingencies, many of which are beyond the control of Evotec. Evotec expressly disclaims any obligations or undertaking to release publicly any updates or revisions to any forward-looking statements contained herein to reflect any change in Evotec’s expectations with respect thereto or any change in events, conditions or circumstances on which any statement is based.